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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFAP All Species: 13.64
Human Site: S398 Identified Species: 37.5
UniProt: P14136 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14136 NP_001124491.1 432 49880 S398 E T S L D T K S V S E G H L K
Chimpanzee Pan troglodytes Q5R1W8 466 53634 P432 E T N L D S L P L V D T H S K
Rhesus Macaque Macaca mulatta XP_001102095 360 41153 V327 T S L D T K S V S E G H L K R
Dog Lupus familis XP_848378 433 49999 S399 E T S L D T K S V S E G H L K
Cat Felis silvestris
Mouse Mus musculus P03995 430 49882 S395 E T S L D T K S V S E G H L K
Rat Rattus norvegicus P47819 430 49939 S396 E T S L D T K S V S E G H L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09654 460 53124 P426 E T N I E S Q P I V D T H S K
Frog Xenopus laevis P24790 463 53478 P426 E T N L D S H P V D T H S K R
Zebra Danio Brachydanio rerio Q58EE9 444 51231 L410 D T S M D T K L T P E A H V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.5 78.4 93.5 N.A. 91.1 91.4 N.A. N.A. 53.7 53.7 66.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 74.6 80.3 96 N.A. 95.8 94.9 N.A. N.A. 75 73.2 77.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 0 100 N.A. 100 100 N.A. N.A. 26.6 33.3 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 13.3 100 N.A. 100 100 N.A. N.A. 73.3 53.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 12 78 0 0 0 0 12 23 0 0 0 0 % D
% Glu: 78 0 0 0 12 0 0 0 0 12 56 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 12 45 0 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 23 78 0 0 % H
% Ile: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 12 56 0 0 0 0 0 0 23 78 % K
% Leu: 0 0 12 67 0 0 12 12 12 0 0 0 12 45 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 34 0 12 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % R
% Ser: 0 12 56 0 0 34 12 45 12 45 0 0 12 23 0 % S
% Thr: 12 89 0 0 12 56 0 0 12 0 12 23 0 0 0 % T
% Val: 0 0 0 0 0 0 0 12 56 23 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _